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Shawn Demehri

Physician · Massachusetts General Hospital

Credentials: · · · · ·

History

Massachusetts General Hospital
Present

Dermatology
Barnes-Jewish Hospital
2011–2014
Internal Medicine
St Luke's Hospital
2010–2011
Washington University in St. Louis
Washington University School of Medicine
2006–2010
Washington State University
2002–2006

Research

CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity
Nature Biotechnology · 2019 · 499 citations
High-sensitivity detection of BCR-ABL kinase domain mutations in imatinib-naive patients: correlation with clonal cytogenetic evolution but not response to therapy
Blood · 2005 · 255 citations
Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment
Cancer Cell · 2009 · First of 3 authors · 229 citations

MA
Marjan Azin
29 papers · 11 as a resident
Eugene Semenov
14 papers · 1 as a resident
Rosalynn Nazarian
11 papers
AA
Amir Ameri
9 papers · 9 as a resident
KR
Kerry Reynolds
8 papers
John Strickley
7 papers · 4 as a resident
Lynn Cornelius
7 papers
Maryam Asgari
7 papers
Bonnie Leung
6 papers · 4 as a resident
Brian Druker
6 papers
Michael Deininger
6 papers
NL
Nicole LeBoeuf
6 papers

Grants

Cancer Immunoprevention Network (CIP-Net) Resource Coordinating Center
National Cancer Institute · U24
PI · $1.6M · Roswell Park Cancer Institute Corp
2025–2030
Immunosurveillance of Breast Glands with Oncogenic Germline Mutations
National Cancer Institute · UH3
Contact PI · $892.8K · Massachusetts General Hospital
2024–2029
Interplay of Natural Killer Cells and Extracellular Matrix Proteins in Solid Cancers
National Cancer Institute · R01
Contact PI · $2M · Massachusetts General Hospital
2024–2029
Interleukin 33 Regulation for Cancer Prevention in Chronic Inflammation
National Cancer Institute · R01
Contact PI · $1.8M · Massachusetts General Hospital
2024–2029

Clinical trials

Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients
Principal investigator · Withdrawn · Phase 2
Massachusetts General Hospital
2026–2030
Immunotherapy After Transplantation for Skin Cancer Prevention in Organ Transplant Recipients
Principal investigator · Withdrawn · Phase 2
Massachusetts General Hospital
2026–2030
Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients
Principal investigator · Active not recruiting · Phase 2
University of Arizona
2024–2029
Topical Calcipotriene Treatment for Breast Cancer Immunoprevention
Principal investigator · Terminated · Phase 1
Massachusetts General Hospital
2018–2020