Sridhar Mani
Professor, Department of Oncology · Montefiore Medical Center/Albert Einstein College of Medicine
Credentials: · ·
History
Medical Oncology
Internal Medicine
Research
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
Science · 2015 · 2,807 citations
Alleviating cancer drug toxicity by inhibiting a bacterial enzyme
Science · 2010 · 844 citations
Immunity · 2014 · Last of 19 authors · Corresponding · 840 citations
26 papers
19 papers
13 papers
11 papers
- ME
11 papers
- RR
11 papers
- NV
10 papers
- CT
9 papers
Grants
- 2019–2029
Developmental Flame Retardant Exposure, Gut Microbiome, and Obesity
National Institute of Environmental Health Sciences · R01
PI · $5M · Oregon State University
- 2018–2024
Microbial Metabolite Mimics, PXR and Colitis-Induced Colorectal Cancer
National Cancer Institute · R01
Contact PI · $2.3M · Albert Einstein College of Medicine
- 2012–2018
Development of Novel Drugs to Alleviate CPT-11 Toxicity
National Cancer Institute · R01
Contact PI · $1.6M · Albert Einstein College of Medicine, Inc
- 2009–2015
Chemical Modulation of Orphan Nuclear Receptor Function
National Cancer Institute · R01
Contact PI · $1.6M · Albert Einstein College of Medicine
Clinical trials
- 2015–2019
Principal investigator · Completed
Albert Einstein College of Medicine
- 2010–2011
Safety of 24-hour Infusion of ON 01910.Na in Combination With Gemcitabine in Advanced Solid Tumors
Principal investigator · Completed · Phase 1
Traws Pharma, Inc.
- 2008–2011
Safety Study of ON 01910.Na in Combination With Irinotecan or Oxaliplatin
Principal investigator · Completed · Phase 1
Traws Pharma, Inc.
- 2006–2011
Safety of 24-Hour Infusion of ON 01910.Na in Patients With Advanced Cancer
Principal investigator · Completed · Phase 1
Traws Pharma, Inc.