Steven Laizure
Professor · University of Tennessee College of Medicine
Credentials: · ·
History
Research
The role of human carboxylesterases in drug metabolism: have we overlooked their importance?
Review · Pharmacotherapy · 2013 · First of 5 authors · Corresponding · 348 citations
Bupropion in depression. II. The role of metabolites in clinical outcome
Archives of General Psychiatry · 1988 · 118 citations
Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis
Drug Metabolism and Disposition · 2014 · First of 4 authors · 79 citations
- RP
29 papers
- WH
3 papers
Joanna Laizure
2 papers
- JS
2 papers · 1 as a fellow
1 paper
- BK
1 paper
- DL
1 paper
1 paper
Grants
- 2020–2023
The Inhibition and Transesterification of Dimethyl Fumarate by Ethanol
National Institute of Neurological Disorders and Stroke · R03
Contact PI · $152K · University of Tennessee Health Sci Ctr
- 2014–2017
Caffeine Disposition After Inhalation
National Institute on Drug Abuse · R03
Contact PI · $148.9K · University of Tennessee Health Sci Ctr
- 2011–2013
Inhibition of Carboxylesterase Metabolism by Ethanol
National Institute of General Medical Sciences · R15
PI · $299.6K · University of Tennessee Health Sci Ctr
- 2000–2003
Nalmefene Controlled Release Implantable Pellet
National Institute on Alcohol Abuse and Alcoholism · R15
Contact PI · $142K · University of Tennessee Health Sci Ctr
Clinical trials
- 2014–2017
- 2012
Alcohol Inhibits Drug Metabolism by Carboxylesterases
Principal investigator · Completed · Phase 1
University of Tennessee