Tatsuo Kawai

Director, Legorreta Center for Clinical Transplant Tolerance · Mass General Brigham

Credentials: · · · ·

History

Legorreta Center for Clinical Transplant Tolerance · Mass General Brigham
Present
Mass General Brigham
Present

Preclinical Translation of Kidney, Heart, and Lung Xenotransplantation
National Institute of Allergy and Infectious Diseases · U19
Project lead · $1.8M · Massachusetts General Hospital
2025–2030
Targeting Innate Immunity for Induction of Robust Renal Allograft Tolerance
National Institute of Allergy and Infectious Diseases · U01
Contact PI · $4.3M · Massachusetts General Hospital
2023–2028
Bcl-2 and Mcl-1 Inhibition for Induction of Hematopoietic Chimerism and Renal Allograft Tolerance Without Myelosuppression in Nonhuman Primates
National Institute of Allergy and Infectious Diseases · R01
Contact PI · $4.6M · Massachusetts General Hospital
2022–2027
Mcl-1 Inhibition for Induction of Hematopoietic Chimerism Without Nonselective Myeloablative Treatments in Nonhuman Primates
National Institute of Allergy and Infectious Diseases · R21
Contact PI · $449.6K · Massachusetts General Hospital
2021–2023

Tolerance Through Mixed Chimerism (Sip-Tego)
Principal investigator · Recruiting · Early phase 1
Tatsuo Kawai, MD, PhD
2025–2030
Delayed Tolerance Through Mixed Chimerism
Principal investigator · Active not recruiting · Phase 1, Phase 2
Massachusetts General Hospital
2023–2030
Renal Allograft Tolerance Through Mixed Chimerism (Belatacept)
Principal investigator · Completed · Phase 1
Massachusetts General Hospital
2015–2021
Comparison of Bovine Carotid Artery and Expanded Polytetrafluoroethylene (ePTFE) for Permanent Hemodialysis Access
Principal investigator · Completed
Massachusetts General Hospital
2006–2009