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Wendell Yarbrough

Chair of the Department of Otolaryngology/Head and Neck Surgery · University of North Carolina Hospitals

Credentials: · · · · · · ·

History

Department of Otolaryngology/Head and Neck Surgery · University of North Carolina at Chapel Hill
2018–Present
Department of Otolaryngology/Head and Neck Surgery · University of North Carolina Hospitals
Present
Department of Surgery Section · University of North Carolina Hospitals
Present

University of North Carolina Hospitals
1994–1996
Otolaryngology – Head and Neck Surgery
University of North Carolina Hospitals
1990–1994
General Surgery
University of North Carolina Hospitals
1989–1990
Vanderbilt Owen Graduate School of Management
University of North Carolina School of Medicine
1985–1989

Research

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
Cell · 1998 · Last of 3 authors · 1,368 citations
Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression
Cancer Cell · 2004 · 529 citations
Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas
Journal of Clinical Oncology · 2006 · 458 citations

Benjamin Judson
32 papers
Barbara Burtness
31 papers
Saral Mehra
27 papers
Trevor Hackman
26 papers
AZ
Adam Zanation
22 papers · 5 as a resident
Zain Husain
22 papers
Siddharth Sheth
19 papers
CC
Christine Chung
18 papers · 1 as a fellow
MW
Mark Weissler
18 papers
Henry Park
15 papers · 10 as a resident
Travis Schrank
14 papers
Jeffrey Blumberg
13 papers

Grants

Dissecting NF-kB Pathway in HPV-Associated Head and Neck Cancer
National Institute of Dental and Craniofacial Research · R01
Contact PI · $2M · Univ of North Carolina Chapel Hill
2023–2027
Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers for Diagnosis and Treatment of HPV-Associated OPSCC
National Institute of Dental and Craniofacial Research · U01
Contact PI · $3.8M · Univ of North Carolina Chapel Hill
2020–2027
Exploring Mechanisms of Therapeutic Demethylation Effects in HPV-Associated Head and Neck Cancer
National Institute of Dental and Craniofacial Research · R01
Contact PI · $2.1M · Univ of North Carolina Chapel Hill
2019–2024
Tumor Suppressor Qualities and Mechanisms of LZAP Activity
National Institute of Dental and Craniofacial Research · R01
Contact PI · $4.9M · Yale University
2000–2018

Clinical trials

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC
Principal investigator · Recruiting
UNC Lineberger Comprehensive Cancer Center
2020–2033
P53 Mutational Status and cf HPV DNA for the Management of HPV-associated OPSCC
Principal investigator · Completed · Phase 2
UNC Lineberger Comprehensive Cancer Center
2016–2022
DNA Analysis of Tumor Tissue Samples From Patients With Human Papilloma Virus-Associated Cancer of the Oropharynx
Study chair · Completed
Vanderbilt University Medical Center
2006
Study of Proteins in Head and Neck Cancer Cells
Study chair · Completed
Vanderbilt University Medical Center
2005