Yun Yen
Physician · CITY OF HOPE MEDICAL GROUP INC
Credentials: · · ·
History
- Present
CITY OF HOPE MEDICAL GROUP INC

- 1978–1982
Research
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
Nature · 2010 · 1,839 citations
Cancer-secreted miR-105 destroys vascular endothelial barriers to promote metastasis
Cancer Cell · 2014 · 1,242 citations
NCCN clinical practice guidelines in oncology: hepatobiliary cancers
Journal of the National Comprehensive Cancer Network · 2009 · 526 citations
- PC
43 papers
- GS
34 papers

26 papers

25 papers

25 papers
- LL
25 papers
- SS
25 papers
- LX
22 papers · 3 as a resident
Grants
- 2008–2013
Drug Development of Ribonucleotide Reductase Inhibitor
National Cancer Institute · R01
Contact PI · $1.4M · Beckman Research Institute/City of Hope
- 2009–2012
Ultrahigh Sensitive, Personalized Monitoring of Lymphoma Relapse Using Blood Spec
National Cancer Institute · R21
Contact PI · $401.7K · Beckman Research Institute/City of Hope
- 1997–2007
The Role of RR in Chemotherapeutic Drug Resistance
National Cancer Institute · R01
Contact PI · $1M · Beckman Research Institute/City of Hope
- 2004–2006
Genetic Basis of Colon Adenoma Synchronous to Carcinoma.
National Cancer Institute · R03
Contact PI · $172K · Beckman Research Institute/City of Hope
Clinical trials
- 2008–2012
Safety Study of CALAA-01 to Treat Solid Tumor Cancers
Principal investigator · Terminated · Phase 1
Calando Pharmaceuticals
- 2006
3-AP in Treating Patients With Advanced or Metastatic Solid Tumors
Principal investigator · Completed · Phase 1
National Cancer Institute (NCI)
- 2006–2014
A Study of Oxaliplatin and Capecitabine in Unresectable Metastatic Hepatocellular Cancer
Principal investigator · Terminated · Phase 2
City of Hope Medical Center
- 2006–2012
Study of CRLX101 (NLG207) in the Treatment of Advanced Solid Tumors
Principal investigator · Completed · Phase 1, Phase 2
NewLink Genetics Corporation
