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Zuzana Tothova

, in the Basic/Translational Research Junior Faculty Scholars Category · Mass General Brigham

Credentials: · · · · ·

History

Mass General Brigham
Present
Mass General Brigham
Present

Hematology and Medical Oncology
Dana-Farber Cancer Institute
2012–2015
Internal Medicine
Brigham and Women's Hospital
2009–2012
Harvard Medical School
2005–2009

Research

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
Nature Biotechnology · 2016 · 3,532 citations
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
Cell · 2007 · First of 14 authors · 1,278 citations
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation
Nature Biotechnology · 2014 · 1,219 citations

DG
Dwight Gilliland
11 papers
Ben Ebert
9 papers
Elizabeth Morgan
5 papers
DS
David Scadden
3 papers
DS
David Steensma
2 papers
Diego Castrillon
2 papers
Jacqueline Garcia
2 papers
Jon Aster
2 papers
Julie Haydu
2 papers · 1 as a fellow
Marlise Luskin
2 papers
MD
Melanie Donahue
2 papers · 2 as a resident
RP
Rishi Puram
2 papers · 1 as a resident

Grants

Development of Novel Therapeutic Strategies in Human Leukemias
National Cancer Institute · P01
Project lead · $768.6K · Dana-Farber Cancer Inst
1997–2030
Molecular Mechanisms of Splicing Dependency in Cohesin-Mutant Myelodysplasia
National Heart, Lung, and Blood Institute · R01
Contact PI · $1.3M · Dana-Farber Cancer Inst
2023–2028
Investigating the Mechanisms of Cohesinopathy in Myelodysplastic Syndromes
National Heart, Lung, and Blood Institute · K08
Contact PI · $443.6K · Dana-Farber Cancer Inst
2018–2021