Residency · Wilmington, DE
Sponsored by Christiana Care Health Services Inc
Tropism of SARS-CoV-2 for human cortical astrocytes.
Proceedings of the National Academy of Sciences of the United States of America · 2022 · 141 citations · David Shin
Single-cell epigenomics reveals mechanisms of human cortical development.
Nature · 2021 · 241 citations · David Shin
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids.
Cell stem cell · 2021 · 176 citations · David Shin
Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy.
Science advances · 2024 · 47 citations · David Shin
Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders.
Cell stem cell · 2024 · 43 citations · David Shin
Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices.
Nature neuroscience · 2024 · 34 citations · David Shin
Spatiotemporal molecular dynamics of the developing human thalamus.
Science (New York, N.Y.) · 2023 · 61 citations · David Shin
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience.
Neuron · 2021 · 68 citations · David Shin