Residency · The Woodlands, TX
Sponsored by Houston Methodist Hospital
Complex I inhibitor of oxidative phosphorylation in advanced solid tumors and acute myeloid leukemia: phase I trials.
Nature medicine · 2023 · 334 citations · Qi Tatarata
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia.
Signal transduction and targeted therapy · 2022 · 177 citations · Qi Tatarata
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia.
Blood · 2023 · 115 citations · Qi Tatarata
Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models.
Haematologica · 2021 · 123 citations · Qi Tatarata
Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity.
Nature communications · 2021 · 121 citations · Qi Tatarata
Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2-mutated post-MPN AML.
Blood · 2025 · 24 citations · Qi Tatarata
Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells.
Haematologica · 2023 · 64 citations · Qi Tatarata
Exogenous mitochondrial transfer and endogenous mitochondrial fission facilitate AML resistance to OxPhos inhibition.
Blood advances · 2021 · 75 citations · Qi Tatarata