Fellowship · New Haven, CT
Sponsored by Yale-New Haven Hospital
Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity.
Immunity · 2024 · 119 citations · Lee Denson
Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial.
The lancet. Gastroenterology & hepatology · 2022 · 154 citations · Saul Karpen
Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study.
Hepatology (Baltimore, Md.) · 2023 · 77 citations · Rima Fawaz, Saul Karpen
Linking microbial genes to plasma and stool metabolites uncovers host-microbial interactions underlying ulcerative colitis disease course.
Cell host & microbe · 2024 · 65 citations · Lee Denson
Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis.
Journal of hepatology · 2024 · 49 citations · Saul Karpen
Defining the serum proteomic signature of hepatic steatosis, inflammation, ballooning and fibrosis in non-alcoholic fatty liver disease.
Journal of hepatology · 2023 · 88 citations ·
The history and future of bile acid therapies.
Journal of hepatology · 2025 · 29 citations · Saul Karpen
Diagnostic accuracy of serum matrix metalloproteinase-7 as a biomarker of biliary atresia in a large North American cohort.
Hepatology (Baltimore, Md.) · 2024 · 34 citations · Saul Karpen