Research affiliation (role unspecified), Diabetes and Obesity Program, Garvan Institute of Medical Research[7]

Journey
Education, training and research through time.
Undergraduate
University of Virginia
Combined degree
University of Pennsylvania
Residency
Hospital of the University of Pennsylvania
Fellowship
University of Pennsylvania
- Observed in a 2015 publicationResearchSydney, Australia
Research affiliation, Diabetes and Obesity Program[7]
Garvan Institute of Medical Research
A 2015 paper gives Murashige a Garvan author affiliation and a Penn present address. It does not establish an appointment title or duration.
- 2015
1 attributed work
- 2018
3 attributed works
- Branched Chain Amino Acids
Annual review of physiology
- RagC phosphorylation autoregulates mTOR complex 1
The EMBO journal
- Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids
Cell metabolism
- Branched Chain Amino Acids
- 2019
1 attributed work
- 2020
2 attributed works
- Comprehensive quantification of fuel use by the failing and nonfailing human heart
Science (New York, N.Y.) · First author
- Noncanonical WNT Activation in Human Right Ventricular Heart Failure
Frontiers in cardiovascular medicine
- Comprehensive quantification of fuel use by the failing and nonfailing human heart
- 2021
- 2022
3 attributed works
- Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure
Cell metabolism · First author
- Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy
Nature cardiovascular research
- Integrated cardiac metabolism in end-stage human heart failure
- Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure
- Estimated 2023-2026ResidencyPhiladelphia, Pennsylvania
Internal Medicine Residency[4][8]
Hospital of the University of Pennsylvania
The 2023 residency match and transition into first-year Penn fellowship in 2026 bound a coherent 2023-2026 residency estimate. Murashige began Penn residency in the 2023 match cycle. She moved directly from residency into Penn cardiovascular fellowship. Penn does not state Murashige's individual residency appointment dates. The endpoints are year-precision estimates rather than exact dates.
Penn's 2023 MSTP match list identifies Internal Medicine at Penn as Murashige's destination; the current fellowship roster independently names HUP as her residency program.
- 2023 match·Matched to Penn Internal Medicine[8]
- 2025
1 attributed work
- Estimated 2026-2029FellowshipPhiladelphia, Pennsylvania
First-year Cardiovascular Disease Fellow[4][11]
A first-year fellow observed in 2026 within Penn's three-year structure corresponds to an estimated 2026 start and 2029 end at year precision. The roster's year label maps to the 2026 training year. Murashige follows the program's standard three-year sequence without interruption. Penn does not publish Murashige's individual appointment dates. The 2029 endpoint is an estimated program boundary, not a confirmed or expected award date.
Penn places Murashige among first-year cardiovascular disease fellows. The displayed 2026-2029 span is estimated from that year label and the program's three-year structure.
- Dates unknownUndergraduateCharlottesville, Virginia
Human Biology undergraduate education[10]
University of Virginia
UVA's Harris Lab identifies Murashige as an undergraduate in the Human Biology program but supplies no dates or exact degree title.
- Full attendance interval unknownCombined degreePhiladelphia, Pennsylvania
MD-PhD education in Cell Biology, Physiology, and Metabolism[3][4][8]
Penn identifies Murashige as a combined-degree MD-PhD student in the CAMB Cell Biology, Physiology, and Metabolism program and Arany Lab. The source chronology distinguishes PhD defense, the 2022 graduate profile, return to medical school, and the 2023 residency match.
- Completed 2022·Completed PhD in the CAMB Cell Biology, Physiology, and Metabolism program[3]
- 2023 match·Matched to Penn Internal Medicine[8]
Completed on 2021-07-15
Graduate educationPhiladelphia, PennsylvaniaPhD thesis defense in Cell and Molecular Biology[9]
Penn MSTP dates Murashige's CAMB thesis defense and names the thesis topic and mentor Zolt Arany.
Works appear by publication year. Their position does not establish where or when the underlying research was performed.
Education and training
Degrees, training periods and the milestones within them.
- Dates unknownUndergraduateCharlottesville, Virginia
Human Biology undergraduate education[10]
University of Virginia
UVA's Harris Lab identifies Murashige as an undergraduate in the Human Biology program but supplies no dates or exact degree title.
- Full attendance interval unknownCombined degreePhiladelphia, Pennsylvania
MD-PhD education in Cell Biology, Physiology, and Metabolism[3][4][8]
Penn identifies Murashige as a combined-degree MD-PhD student in the CAMB Cell Biology, Physiology, and Metabolism program and Arany Lab. The source chronology distinguishes PhD defense, the 2022 graduate profile, return to medical school, and the 2023 residency match.
- Completed 2022·Completed PhD in the CAMB Cell Biology, Physiology, and Metabolism program[3]
- 2023 match·Matched to Penn Internal Medicine[8]
Completed on 2021-07-15
Graduate educationPhiladelphia, PennsylvaniaPhD thesis defense in Cell and Molecular Biology[9]
Penn MSTP dates Murashige's CAMB thesis defense and names the thesis topic and mentor Zolt Arany.
- Estimated 2023-2026ResidencyPhiladelphia, Pennsylvania
Internal Medicine Residency[4][8]
Hospital of the University of Pennsylvania
The 2023 residency match and transition into first-year Penn fellowship in 2026 bound a coherent 2023-2026 residency estimate. Murashige began Penn residency in the 2023 match cycle. She moved directly from residency into Penn cardiovascular fellowship. Penn does not state Murashige's individual residency appointment dates. The endpoints are year-precision estimates rather than exact dates.
Penn's 2023 MSTP match list identifies Internal Medicine at Penn as Murashige's destination; the current fellowship roster independently names HUP as her residency program.
- 2023 match·Matched to Penn Internal Medicine[8]
- Estimated 2026-2029FellowshipPhiladelphia, Pennsylvania
First-year Cardiovascular Disease Fellow[4][11]
A first-year fellow observed in 2026 within Penn's three-year structure corresponds to an estimated 2026 start and 2029 end at year precision. The roster's year label maps to the 2026 training year. Murashige follows the program's standard three-year sequence without interruption. Penn does not publish Murashige's individual appointment dates. The 2029 endpoint is an estimated program boundary, not a confirmed or expected award date.
Penn places Murashige among first-year cardiovascular disease fellows. The displayed 2026-2029 span is estimated from that year label and the program's three-year structure.
Research
Cardiac metabolism in human heart failure, including systemic branched-chain amino acid metabolism as a potential therapeutic target[3]
Through 2022
Publications
13 attributed works · 4 first author. Counts reflect resolved authorship and may be incomplete.
- 2025
- 2022Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failureCell metabolismfirst authorPMID 36223763
- 2022Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathyNature cardiovascular researchPMID 36776621
- 2020Comprehensive quantification of fuel use by the failing and nonfailing human heartScience (New York, N.Y.)first authorPMID 33060364
- 2020Noncanonical WNT Activation in Human Right Ventricular Heart FailureFrontiers in cardiovascular medicinePMID 33134326
- 2018Branched Chain Amino AcidsAnnual review of physiologyPMID 30485760
- 2018RagC phosphorylation autoregulates mTOR complex 1The EMBO journalPMID 30552228
- 2018Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino AcidsCell metabolismPMID 30449684
- 2015A Positive Feedback Loop between Akt and mTORC2 via SIN1 PhosphorylationCell reportsPMID 26235620
Sources
Sources are listed once and connected to each accepted claim they support. Excerpts preserve the source language used in the review.
- [1]OpenAlex works for author A5063999120
6 source claims · Reviewed Sep 5, 2026
Attributed work: Abstract 100: Integrated Cardiac Metabolism In End-Stage Human Heart Failure | DOI 10.1161/res.129.suppl_1.100 | conference abstract
Sep 3, 2021
A5063999120 authorship; DOI 10.1161/res.129.suppl_1.100; publication_date 2021-09-03
Attributed work: Abstract 562: Comprehensive Arteriovenous Metabolomics in the Human Heart | DOI 10.1161/res.125.suppl_1.562 | conference abstract
Aug 2, 2019
A5063999120 authorship; DOI 10.1161/res.125.suppl_1.562; publication_date 2019-08-02
Attributed work: Abstract P388: Extra-cardiac BCAA Catabolism Lowers Blood Pressure And Protects From Heart Failure | DOI 10.1161/res.129.suppl_1.p388 | conference abstract
Sep 3, 2021
A5063999120 authorship; DOI 10.1161/res.129.suppl_1.p388; publication_date 2021-09-03
Attributed work: Genes of the fatty acid oxidation pathway are upregulated in female as compared to male cardiomyocytes | DOI 10.1101/2024.05.29.594850 | preprint
Jun 2, 2024
A5063999120 authorship with raw_orcid 0000-0001-6486-5538; DOI 10.1101/2024.05.29.594850; publication_date 2024-06-02
Attributed work: Integrated cardiac metabolism in end-stage human heart failure | DOI 10.1016/j.yjmcc.2022.08.232 | conference article
Dec 1, 2022
A5063999120 authorship; DOI 10.1016/j.yjmcc.2022.08.232; publication_date 2022-12-01
Attributed work: Noncanonical WNT activation in human right ventricular heart failure | DOI 10.1101/2020.07.03.20134965 | preprint
Jul 6, 2020
A5063999120 authorship; DOI 10.1101/2020.07.03.20134965; publication_date 2020-07-06
- [2]PubMed records for Murashige D author results (9 records)
9 source claims · Reviewed Sep 5, 2026
Attributed work: A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation | DOI 10.1016/j.celrep.2015.07.016 | PMID 26235620
Jul 30, 2015
PMID 26235620 ... Danielle S Murashige ... Diabetes and Obesity Program, Garvan Institute of Medical Research
Attributed work: Branched Chain Amino Acids | DOI 10.1146/annurev-physiol-020518-114455 | PMID 30485760
Nov 28, 2018
PMID 30485760 ... Michael Neinast, Danielle Murashige, Zoltan Arany
Attributed work: Comprehensive quantification of fuel use by the failing and nonfailing human heart | DOI 10.1126/science.abc8861 | PMID 33060364
Oct 16, 2020
PMID 33060364 ... Danielle Murashige ... first author
Attributed work: Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure | DOI 10.1016/j.cmet.2022.09.008 | PMID 36223763
Oct 11, 2022
PMID 36223763 ... Danielle Murashige ... first author
Attributed work: Genes of the Fatty Acid Oxidation Pathway are Upregulated in Female as Compared to Male Cardiomyocytes | DOI 10.1161/CIRCULATIONAHA.124.071973 | PMID 39960981
Feb 18, 2025
PMID 39960981 ... Danielle S Murashige ... Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania
Attributed work: Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy | DOI 10.1038/s44161-022-00117-6 | PMID 36776621
Aug 29, 2022
PMID 36776621 ... Danielle Murashige ... Perelman School of Medicine, Cardiovascular Institute, University of Pennsylvania
Attributed work: Noncanonical WNT Activation in Human Right Ventricular Heart Failure | DOI 10.3389/fcvm.2020.582407 | PMID 33134326
Oct 7, 2020
PMID 33134326 ... Danielle Murashige ... University of Pennsylvania cardiovascular coauthor group
Attributed work: Quantitative Analysis of the Whole-Body Metabolic Fate of Branched-Chain Amino Acids | DOI 10.1016/j.cmet.2018.10.013 | PMID 30449684
Nov 15, 2018
PMID 30449684 ... Danielle S Murashige ... Perelman School of Medicine, University of Pennsylvania
Attributed work: RagC phosphorylation autoregulates mTOR complex 1 | DOI 10.15252/embj.201899548 | PMID 30552228
Dec 14, 2018
PMID 30552228 ... Danielle S Murashige ... Perelman School of Medicine, University of Pennsylvania
- [3]Celebrating CAMB Graduates | Biomedical Graduate Studies
5 source claims · 3 journey details · Reviewed Sep 5, 2026
MD-PhD education in Cell Biology, Physiology, and Metabolism: Full attendance interval unknown. Penn identifies Murashige as a combined-degree MD-PhD student in the CAMB Cell Biology, Physiology, and Metabolism program and Arany Lab. The source chronology distinguishes PhD defense, the 2022 graduate profile, return to medical school, and the 2023 residency match.
Completed PhD in the CAMB Cell Biology, Physiology, and Metabolism program: 2022
The 2021 thesis defense and 2022 CAMB graduate profile describe different events. The journey preserves both and does not convert either into a complete MD-PhD attendance interval.
Biographical context: PhD thesis: Comprehensive fuel metabolism of the human heart and the role for enhancing branched-chain amino acid catabolism in protection against heart failure
Through 2022
Thesis Title: Comprehensive fuel metabolism of the human heart and the role for enhancing branched-chain amino acid catabolism in protection against heart failure
Graduate education: University of Pennsylvania, Cell Biology, Physiology, and Metabolism Program (PhD; Arany Lab)
Through 2022
Combined Degree, MD-PhD ... Danielle Murashige ... Cell Biology, Physiology, and Metabolism Program ... Danielle did her PhD in the Arany lab
Official headshot: Portrait
2022
The responsive image source murashige.6e590ad8.jpg immediately precedes the Danielle Murashige graduate profile.
Official profile: Official profile
Danielle Murashige | Mentor: Zoltan Arany, MD, PhD | Cell Biology, Physiology, and Metabolism Program
Research interests: Cardiac metabolism in human heart failure, including systemic branched-chain amino acid metabolism as a potential therapeutic target
Through 2022
Danielle's thesis work focused on reprogramming of cardiac metabolism in human heart failure and how targeting systemic BCAA metabolism might be leveraged for HF treatment
- [4]Reviewed current trainee roster
2 source claims · 3 journey details · Reviewed Sep 5, 2026
MD-PhD education in Cell Biology, Physiology, and Metabolism: Full attendance interval unknown. Penn identifies Murashige as a combined-degree MD-PhD student in the CAMB Cell Biology, Physiology, and Metabolism program and Arany Lab. The source chronology distinguishes PhD defense, the 2022 graduate profile, return to medical school, and the 2023 residency match.
Internal Medicine Residency: Estimated 2023-2026. Penn's 2023 MSTP match list identifies Internal Medicine at Penn as Murashige's destination; the current fellowship roster independently names HUP as her residency program.
First-year Cardiovascular Disease Fellow: Estimated 2026-2029. Penn places Murashige among first-year cardiovascular disease fellows. The displayed 2026-2029 span is estimated from that year label and the program's three-year structure.
Fellowship: Cardiovascular Disease Fellowship, University of Pennsylvania
1st year fellows ... Danielle Murashige, MD, PhD
Medical school: Perelman School of Medicine, University of Pennsylvania (MD)
Danielle Murashige, MD, PhD | Medical School: Perelman School of Medicine, University of Pennsylvania
- [5]OpenAlex author A5063999120 | Danielle Murashige
1 source claim · Reviewed Sep 5, 2026
Official profile: Official profile
display_name: Danielle Murashige; orcid: https://orcid.org/0000-0001-6486-5538
- [6]ORCID record 0000-0001-6486-5538 | Danielle Murashige
1 source claim · Reviewed Sep 5, 2026
Official profile: Official profile
given-names: Danielle; family-name: Murashige; path: 0000-0001-6486-5538
- [7]A Positive Feedback Loop between Akt and mTORC2 via SIN1 Phosphorylation
1 source claim · 2 journey details · Reviewed Sep 5, 2026
Research affiliation, Diabetes and Obesity Program: Observed in a 2015 publication. A 2015 paper gives Murashige a Garvan author affiliation and a Penn present address. It does not establish an appointment title or duration.
The 2015 Garvan affiliation and Penn present address establish an observed affiliation point, not a Garvan employment duration or title.
Research affiliation: Research affiliation (role unspecified), Diabetes and Obesity Program, Garvan Institute of Medical Research
Danielle S. Murashige ... Diabetes and Obesity Program, Garvan Institute of Medical Research ... co-first author ... Present address: Perelman School of Medicine, University of Pennsylvania
- [8]Residency Match Lists | Penn Medical Scientist Training Program
1 source claim · 3 journey details · Reviewed Sep 5, 2026
MD-PhD education in Cell Biology, Physiology, and Metabolism: Full attendance interval unknown. Penn identifies Murashige as a combined-degree MD-PhD student in the CAMB Cell Biology, Physiology, and Metabolism program and Arany Lab. The source chronology distinguishes PhD defense, the 2022 graduate profile, return to medical school, and the 2023 residency match.
Matched to Penn Internal Medicine: 2023 match
Internal Medicine Residency: Estimated 2023-2026. Penn's 2023 MSTP match list identifies Internal Medicine at Penn as Murashige's destination; the current fellowship roster independently names HUP as her residency program.
Residency: Internal Medicine Residency, Hospital of the University of Pennsylvania
Match List 2023 ... Danielle Murashige | internal medicine | Penn
- [9]Thesis Defenses | Penn Medical Scientist Training Program
1 source claim · 2 journey details · Reviewed Sep 5, 2026
PhD thesis defense in Cell and Molecular Biology: Completed on 2021-07-15. Penn MSTP dates Murashige's CAMB thesis defense and names the thesis topic and mentor Zolt Arany.
The 2021 thesis defense and 2022 CAMB graduate profile describe different events. The journey preserves both and does not convert either into a complete MD-PhD attendance interval.
Thesis defense: PhD thesis defense, Cell and Molecular Biology, University of Pennsylvania
Jul 15, 2021
2020-2021 | July 2021 | Danielle Murashige (CAMB) | July 15, 1:00 | Title: Comprehensive fuel metabolism of the human heart and how promotion of non-cardiac BCAA catabolism protects against heart failure | Mentor: Dr. Zolt Arany
- [10]Latest News | Harris Lab, University of Virginia
1 source claim · 1 journey details · Reviewed Sep 5, 2026
Human Biology undergraduate education: Dates unknown. UVA's Harris Lab identifies Murashige as an undergraduate in the Human Biology program but supplies no dates or exact degree title.
Undergraduate education: University of Virginia, Human Biology program (undergraduate; exact degree not established by retained primary source)
Former Harris lab undergraduate Danielle Murashige ... performed research in the Harris lab for several years while she was in the Human Biology program at UVA
- [11]About the program | Penn Cardiovascular Disease Fellowship
0 source claims · 1 journey details
First-year Cardiovascular Disease Fellow: Estimated 2026-2029. Penn places Murashige among first-year cardiovascular disease fellows. The displayed 2026-2029 span is estimated from that year label and the program's three-year structure.