Adam Worthalter
Associate Professor of Neurological Surgery · McGaw Medical Center of Northwestern University
Credentials: · · ·
History
Research
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Nature Medicine · 2019 · 762 citations
Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
Nature Medicine · 2023 · 266 citations
Science Translational Medicine · 2021 · 265 citations
52 papers
35 papers
34 papers
31 papers
26 papers
25 papers
24 papers
18 papers
Grants
- 2020–2031
National Cancer Institute · R01
Contact PI · $2.8M · Northwestern University
- 2021–2027
Advancing Treatment and Understanding of Immunotherapy in Glioblastoma
National Cancer Institute · U19
Project lead · $2.1M · University of California, San Francisco
- 2020–2025
MAPK as Target of Glioma Immunoediting by CD8 T-Cells, and Predictor of Response to Immunotherapy
National Institute of Neurological Disorders and Stroke · R01
Contact PI · $1.9M · Northwestern University
- 2015–2021
TOP2A Effects on Transcription in Gliomas: Implications for Personalized Therapy
NIH Office of the Director · DP5
Contact PI · $2M · Northwestern University
Clinical trials
- 2024–2031
Phase 2a Immune Modulation With Ultrasound for Newly Diagnosed Glioblastoma
Principal investigator · Recruiting · Phase 2
Northwestern University
- 2020–2026
Principal investigator · Active not recruiting · Phase 1, Phase 2
Northwestern University