Jeffrey Bruce
Vice Chairman of Academic Affairs · New York Presbyterian Hospital
Credentials: · · · ·
History
- Present
Brain Tumor Center · New York Presbyterian Hospital
- 1979–1983
UMDNJ - Robert Wood Johnson School of Medicine
Research
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Nature Medicine · 2019 · 762 citations
European Journal of Cancer · 2012 · 661 citations
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
Science · 2007 · 606 citations
145 papers
65 papers
60 papers
37 papers
34 papers · 17 as a resident
29 papers
- PF
27 papers
25 papers · 22 as a resident
Grants
- 2017–2028
Single Cell Analysis of the Infiltrative Margins of Glioblastoma and Post Treatment Recurrence
National Institute of Neurological Disorders and Stroke · R01
Contact PI · $4.3M · Columbia University Health Sciences
- 2012–2019
Chronic Convection Enhanced Delivery (Ced) of Topotecan for Glioblastoma
National Cancer Institute · R01
Contact PI · $2.9M · Columbia University Health Sciences
- 2002–2010
Topotecan by Intracerebral Clysis for Brain Tumors
National Cancer Institute · R01
Contact PI · $2.3M · Columbia University Health Sciences
- 1997–2005
General Clinical Research Center
National Center for Research Resources · M01
Project lead · $775.4K · Columbia University Health Sciences
Clinical trials
- 2026–2028
Chronic CED of TPT for Recurrent Malignant Glioma
Principal investigator · Recruiting · Phase 1
Jeffrey N. Bruce
- 2018–2021
Chronic Convection Enhanced Delivery of Topotecan
Principal investigator · Completed · Phase 1
Columbia University
- 2004–2016
Topotecan by Intracerebral Clysis for Recurrent Primary Malignant Brain Tumors
Principal investigator · Completed · Phase 1
Columbia University