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Brian Ladle

Assistant Professor of Oncology · Johns Hopkins University School of Medicine

Credentials: · · ·

History

Johns Hopkins University School of Medicine
Present

Hematology and Medical Oncology
2010–2013
Internal Medicine
2007–2010
Johns Hopkins Univ Sch of Med
2003–2007

Research

Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response
The Journal of Experimental Medicine · 2005 · 315 citations
Atezolizumab for Advanced Alveolar Soft Part Sarcoma
New England Journal of Medicine · 2023 · 144 citations
De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation
Proceedings of the National Academy of Sciences of the United States of America · 2016 · First of 9 authors · Corresponding · 131 citations

NL
Nicolas Llosa
9 papers
AL
Adam Levin
7 papers
Christine Pratilas
7 papers
CM
Carol Morris
5 papers
Daniel Rhee
5 papers
Elizabeth Jaffee
5 papers
Christian Meyer
4 papers
Robert Anders
4 papers
CG
Christopher Gamper
3 papers
ER
Erin Resch
3 papers
John Gross
3 papers
John Ligon
3 papers · 3 as a fellow

Grants

MRI-Guided Cryoablation and Imaging-Guided Intratumoral Delivery of STING Agonist Immunotherapy to Target Localized and Metastatic Canine Osteosarcoma
National Cancer Institute · R01
PI · $3.1M · Johns Hopkins University
2020–2027

Clinical trials

Combination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma
Principal investigator · Terminated · Phase 2
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2013–2017
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Site PI · Recruiting · Phase 3
Children's Oncology Group
2022–2031