David Matuskey
Director, NeuroPET Imaging Program, Radiology and Biomedical Imaging · Yale-New Haven Hospital
Credentials: · ·
History
PresentYale Positron Emission Tomography (PET) Center · Yale-New Haven Hospital
Present
Present
- 2009–2010
Geriatric Psychiatry
2005–2009
1997–2001
Research
Imaging synaptic density in the living human brain
Science Translational Medicine · 2016 · 437 citations
Lower synaptic density is associated with depression severity and network alterations
Nature Communications · 2019 · 395 citations
Imaging robust microglial activation after lipopolysaccharide administration in humans with PET
Proceedings of the National Academy of Sciences of the United States of America · 2015 · 290 citations

26 papers
- RM
17 papers
- MP
16 papers
- RR
16 papers

14 papers
- DD
11 papers

11 papers

11 papers · 4 as a resident
Grants
- 2025–2030
Imaging Brain Kappa Opioid Receptors in Early Abstinence Opioid Use Disorder
National Institute on Drug Abuse · R01
PI · $1.6M · Yale University
- 2025–2030
National Institute of Neurological Disorders and Stroke · R01
PI · $1.3M · Ut Southwestern Medical Center
- 2022–2027
In vivo Synaptic and Dopamine Transporter Imaging in Parkinson's Disease
National Institute of Neurological Disorders and Stroke · R01
Contact PI · $2.7M · Yale University
- 2021–2025
Novel in vivo Synaptic Imaging in Experienced Meditators
National Center for Complementary and Integrative Health · R21
Contact PI · $460.6K · Yale University
Clinical trials
- 2025
PET and MRI Imaging With Scopolamine at the Muscarinic M1 Receptor
Principal investigator · Withdrawn · Phase 1
Yale University
- 2022–2024
Novel in Vivo Synaptic Imaging in Experienced Meditators
Principal investigator · Completed · Phase 1
Yale University

