Jonathan Ostrem

Assistant Professor · University of California (San Francisco) School of Medicine

Credentials: · · ·

History

University of California (San Francisco) School of Medicine
Present
Mass General Brigham
Present
University of California (San Francisco) School of Medicine
Present

Hematology and Medical Oncology
Mass General Brigham
2019–2022
Internal Medicine
Mass General Brigham
2016–2019
Univ of California, San Francisco Sch of Med
2012–2016

Research

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
Nature · 2013 · First of 5 authors · 2,087 citations
Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design
Review · Nature Reviews Drug Discovery · 2016 · First of 2 authors · 512 citations
OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin
Proceedings of the National Academy of Sciences of the United States of America · 2014 · 193 citations

Eric Haura
1 paper
Jia Luo
1 paper
John Gordan
1 paper
Liza Villaruz
1 paper
Noah Younger
1 paper
Trever Bivona
1 paper
Xiaomin Liang
1 paper