Sign inJoin waitlistJoin the waitlist

Steven Brem

Course Director, Annual Penn Brain Tumor CME · Perelman School of Medicine at the University of Pennsylvania

Credentials: · · · ·

History

Annual Penn Brain Tumor CME · Perelman School of Medicine at the University of Pennsylvania
Present
Surgical Neuro-Oncology Division · University of Pennsylvania Health System
Present
Penn Brain Tumor Center · University of Pennsylvania Health System
Present

Ronald Reagan UCLA Medical Center
1980–1981
NewYork-Presbyterian
1979–1980
Neurological Surgery
Massachusetts General Hospital
1972–1979
Harvard Medical School
1968–1972

Research

Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial
JAMA · 2017 · 2,133 citations
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
Science Translational Medicine · 2017 · 1,567 citations
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor…
The Lancet · 1995 · 1,061 citations

Donald O’Rourke
46 papers
Arati Desai
36 papers
Stephen Bagley
34 papers
Suyash Mohan
26 papers
Kalil Abdullah
16 papers · 9 as a resident
Ronald Wolf
14 papers
Ali Nabavizadeh
13 papers
Robert Lustig
13 papers
MacLean Nasrallah
11 papers
Fraser Henderson
10 papers · 7 as a resident
John Lee
10 papers
Jay Dorsey
9 papers

Grants

Connectomics Meets Neuro-Oncology: Mapping the Brain for Treatment Planning
National Institute of Neurological Disorders and Stroke · R01
PI · $2.7M · University of Pennsylvania
2016–2022
Approaches to Brain Tumor Therapy
National Cancer Institute · U01
Contact PI · $454.5K · University of South Florida
1998–2003
Copper and Angiogenesis Control of Cns Malignancy
National Cancer Institute · R55
Contact PI · $100K · Northwestern University
1992–1994

Clinical trials

Validation of Edema-invariant Multi-shell High Angular Resolution Diffusion Imaging (msHARDI)-Based Tractography With Intra-operative Cortical Stimulation
Principal investigator · Completed
Abramson Cancer Center at Penn Medicine
2014–2022
Penicillamine, Low Copper Diet, and Radiation Therapy in Treating Patients With Glioblastoma
Study chair · Completed · Phase 2
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
1999–2005
Expanded Access Protocol for GBM Patients With Already Manufactured DCVax®-L Who Have Screen-Failed Protocol 020221
Site PI · Available
Northwest Biotherapeutics